For the past decade, the Greenville Health System (GHS) Department of OB/GYN has maintained a team of full-time researchers dedicated solely to studies designed to improve patient care. In some cases, these projects were conceived and implemented by faculty members within Greenville Health System. In other cases, some of the world’s largest and most innovative medical and pharmaceutical companies have enlisted our help to complete clinical trials. Our reputation as a center of excellence in research has allowed us to continue to attract top research projects that offer many free benefits for our patients.
Select from the list of department divisions below to view projects headed by GHS researchers over the past few years.
Clinical Research 2004-2007: Maternal Fetal Medicine
Study
- Novel delivery of progesterone to support pregnancy
- Head-to-head comparison of medications to lower the risk of gestational diabetes
Clinical Research 2004-2007: Urogynecology/Gynecology
Study
- Treatments for overactive bladder
- New surgical techniques for urinary incontinence
- Surgical incision closure with new suture that limits scarring
- New forms of postmenopausal hormone therapy
- New forms of oral contraceptives
- Natural treatments for women without menses
- Novel means for treating women with heavy menses
- Alternatives to surgery for uterine fibroids
Clinical Research 2004-2007 Reproductive Endocrinology & Infertility
Study
- Non-estrogen treatments for menopausal hot flashes
- New injectable forms of fertility medications
- Prevention of surgical adhesions (scar tissue)
- Novel delivery of progesterone to support pregnancy
- Use of new progesterone-like drugs to shrink fibroid tumors
- New ways of freezing eggs to preserve fertility
- Use of testosterone for women with low libido
- Natural treatments for women without menses
- Impact of diet and exercise on overweight, infertile women
Resident Research
All resident physicians in the Department of Obstetrics and Gynecology must complete a prospective research project during the course of their four years of training. The department's strong infrastructure for clinical research is particularly well-suited to assist residents in achieving this requirement. Residents must choose a project and select a mentor during their first year of training, then complete data gathering, analysis, and presentation of results during their subsequent years.
We are proud that physicians training in our department have won the coveted Colin Richardson award for outstanding Ob/Gyn resident research in the nation for two consecutive years (2005 and 2006). Our institution’s commitment to research helps foster a better understanding of human physiology and provides insight into emerging treatments and technology for future obstetricians and gynecologists.
Below is a list of recent Ob/Gyn resident research projects:
Resident Research 2004-2007
- Endometriosis and Interstitial Cystitis: A Blood Test
- L-selectin LIgand Expression in Normal Fertile and Infertile Women
- Efficacy of Vaginal Misoprostol for Labor Induction Depending on Method of Administration
- Prospective, Randomized, Double-blinded, Placebo-controlled Trial Comparing Metronidazole to Standard Antibiotic Prophylaxis for Postoperative Infection Following Hysterectomy
- Complement 3a Association with Endometriosis
- Cyr 61 Expression in Normal and Abnormal Endometrium: A Marker of Estrogenic Activity
- Antimicrobial Susceptibilities of Group B Streptococcus in Antenatal Genital Cultures
- Detection and Characterization of Isolated Androgen Receptor Expression in the Human Endometrial Cancer Cell Line, HEC-1B
- Therapeutic Tocolysis with Magnesium Sulfate in PROM Between 24-32 Weeks Gestation with Concomitant Administration of Antibiotics and Corticosteroids: A Randomized Pilot Study
- Elective Cesarean Section: Adherence to ACOG Guidelines and Neonatal Morbidity
- Factors Associated with Embryo Transfer
- Urinary Incontinence with Sexual Intercourse: A Retrospective Review of Patients in a Community-based Setting
- Are Specific Heart Rate Tracings Predictive of Decreased Fetal Oxygen Saturations Intrapartum?
- A Retrospective Cohort Study on the Relationship of Poly (L-lactide/glycolide) Suture and Wound Complications After Cesarean Section
- The Cancelled ART Patient: Who, What, and Why